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An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which...

詳細記述

書誌詳細
第一著者: Graham L. Patrick
フォーマット: Printed Book
出版事項: Oxford Oxford University Press 2013
版:5th ed
主題:
目次:
  • Drugs and drug targets
  • an overview
  • Drug targets : structure and function
  • Protein structure and function
  • Enzymes: structure and function
  • Receptors: structure and function
  • Receptors and signal transduction
  • Nucleic acids: structure and function
  • Pharmacodynamics and pharmacokinetics
  • Enzymes as drug targets
  • Receptors as drug targets
  • Nucleic acids as drug targets
  • Miscellaneous drug targets
  • Pharmacokinetics and related topics
  • Statins
  • Drug discovery, design, and development
  • Drug discovery: finding a lead
  • Drug design: optimizing target interactions
  • Drug design: optimizing access to the target
  • Getting the drug to market
  • The design of ACE inhibitors
  • Artemisinin and related antimalarial drugs
  • The design of oxamniquine
  • Tools of the trade
  • Combinatorial synthesis
  • Computers in medicinal chemistry
  • Quantitative structure-activity relationships (QSAR)
  • De novo design of a thymidylate synthase inhibitor
  • Selected topics in medicinal chemistry
  • Antibacterial agents
  • Antiviral agents
  • Anticancer agents
  • Cholinergics, anticholinergics, and anticholinesterases
  • Drugs acting on the adrenergic nervous system
  • Opioid analgesics
  • Antiulcer agents
  • Steroidal anti-inflammatory agents
  • Design of a novel antidepressant.