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An Introduction to Medicinal Chemistry
An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which...
| מחבר ראשי: | |
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| פורמט: | Printed Book |
| יצא לאור: |
Oxford
Oxford University Press
2013
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| מהדורה: | 5th ed |
| נושאים: |
תוכן הענינים:
- Drugs and drug targets
- an overview
- Drug targets : structure and function
- Protein structure and function
- Enzymes: structure and function
- Receptors: structure and function
- Receptors and signal transduction
- Nucleic acids: structure and function
- Pharmacodynamics and pharmacokinetics
- Enzymes as drug targets
- Receptors as drug targets
- Nucleic acids as drug targets
- Miscellaneous drug targets
- Pharmacokinetics and related topics
- Statins
- Drug discovery, design, and development
- Drug discovery: finding a lead
- Drug design: optimizing target interactions
- Drug design: optimizing access to the target
- Getting the drug to market
- The design of ACE inhibitors
- Artemisinin and related antimalarial drugs
- The design of oxamniquine
- Tools of the trade
- Combinatorial synthesis
- Computers in medicinal chemistry
- Quantitative structure-activity relationships (QSAR)
- De novo design of a thymidylate synthase inhibitor
- Selected topics in medicinal chemistry
- Antibacterial agents
- Antiviral agents
- Anticancer agents
- Cholinergics, anticholinergics, and anticholinesterases
- Drugs acting on the adrenergic nervous system
- Opioid analgesics
- Antiulcer agents
- Steroidal anti-inflammatory agents
- Design of a novel antidepressant.