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Gene targeting /

This book examines the revolutionary new technology of gene targeting, from its history to its potential application for the genetic treatment of human diseases. It begins with an introduction to the field and a description of the whole gene targeting spectrum. It continues with discussions in the f...

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Bibliographic Details
Other Authors: Vega, Manuel A.
Format: Printed Book
Language:English
Published: Boca Raton, Fla. : CRC Press, c1995.
Subjects:
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060 1 0 |a QH 442  |b G32542 1995 
060 0 0 |a 1995 B-216 
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245 0 0 |a Gene targeting /  |c edited by Manuel A. Vega. 
260 |a Boca Raton, Fla. :  |b CRC Press,  |c c1995. 
300 |a 236 p. :  |b ill. ;  |c 24 cm. 
504 |a Includes bibliographical references and index. 
505 0 |a Gene targeting / Wolf M. Bertling -- Molecular mechanisms of homologous recombination / Alan S. Waldman -- Gene targeting in tripanosomatids / Angela K. Cruz -- Gene targeting in plants / Renuko Offringa, Paul Hooykaas -- Gene targeting in mammalian development and physiology / Thomas Lufkin -- Animal models of human genetic disease / Jean-Louis Guenet -- Homologous recombination proteins and their potential applications in gene targeting technology / Stephen C. Kowalczykowski, David A. Zarling -- Gene targeting in human gene therapy / Manuel A. Vega. 
520 |a This book examines the revolutionary new technology of gene targeting, from its history to its potential application for the genetic treatment of human diseases. It begins with an introduction to the field and a description of the whole gene targeting spectrum. It continues with discussions in the following areas: The molecular mechanisms of the homologous recombination reactions lying behind gene targeting technology The application of gene targeting approaches to the problems of tripanosomatide biology and etiopathology The concept of gene targeting on plant genes and its impact on plant genetic engineering The current knowledge on mammalian development and physiology and its relationship to gene targeting technology The application of gene targeting technology, as well as other genetic techniques, to the production of animal models for human diseases The enzymatic complexes and components participating in natural bacterial DNA recombination and their potential application to gene targeting technology The potential application of gene targeting for the genetic treatment of human diseases 
650 0 |a Genetic engineering 
650 2 |a Gene Targeting. 
700 1 |a Vega, Manuel A. 
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