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999 |c 122382  |d 122382 
020 |a 9781118032169 (hbk.) 
082 0 0 |a 615.704 5  |b Q3 
245 0 0 |a Drug-drug interactions for therapeutic biologics/  |c ed by Honghui Zhou and Bernd Meibohm. 
260 |a New Jersey:  |b John Wiley & Sons,  |c 2013. 
300 |a xv, 361 p., [8] col. plates :  |b some col. ill. ; 
504 |a Includes bibliographical references and index. 
505 0 |a Drug interactions for therapeutic proteins : a journey just beginning / Honghui Zhou, Bernd Meibohm -- Pharmacokinetic and pharmacodynamic-based drug interactions for therapeutic proteins / Dan Lu ... [et al.] -- Drug interaction assessment strategies : small molecules versus therapeutic proteins / Shannon Dallas ... [et al.] -- Model-independent and modeling-based methods to assess drug-drug interactions for therapeutic proteins / Di Wu, Jeffrey Barrett -- Utility of in vitro methods in drug-drug interaction assessment and prediction for therapeutic biologics / Theresa Nguyen, Narendra Kishnani, Raymond Evers -- Use of animal models for projection of clinical drug-drug interactions for therapeutic proteins / Eugenia Kraynov, Martin E. Dowty -- The "cocktail" approach and its utility in drug-drug interaction assessments for therapeutic proteins / Alexander Jetter, Uwe Fuhr -- Logistic considerations in study design for biologic drug-drug interaction assessments / Min Zhu and Yu-Nien (Tom) Sun -- Statistical considerations in assessing drug-drug interactions for therapeutic proteins / Chuanpu Hu and Honghui Zhou -- Scientific perspectives on therapeutic protein drug-drug interaction assessments / Hong Zhao ... [et al.] -- Disease-drug-drug interaction assessments for tocilizumab : a monoclonal antibody against interleukin-6 receptor to treat patients with rheumatoid arthritis / Xuapang Zhang and Barbara J. Brennan -- -- Drug-drug interactions for etanercept : a fusion protein / Joan Korth-Bradley -- Drug interactions of cytokines and anti-cytokine therapeutic proteins / J. Greg Slatter L.C. Wienkers and Leslie J. Dickmann -- Drug interactions for growth factors and hormones / Yow-Ming C. Wang, Tarundeep Kakkar -- Drug-drug interactions for nucleic acid-based derivatires / Jan Wang and Hong Zhao. 
650 1 2 |a Drug interactions.  |9 64504 
650 2 2 |a Drug discovery.  |9 64505 
650 2 2 |a Proteins-Therapeutic use.  |9 64506 
700 1 |a Zhou, Honghui, Ed.  |9 64492 
700 1 |a Meibohm, Bernd, Ed.  |9 64493 
856 |u https://books.google.co.in/books?id=a145e9RT9S4C&printsec=frontcover&dq=Drug-drug+interactions+for+therapeutic+biologics&hl=en&sa=X&ved=0ahUKEwjG98TTxP7WAhXLQI8KHS3-C6gQ6AEIJTAA#v=onepage&q=Drug-drug%20interactions%20for%20therapeutic%20biologics&f=false 
942 |c BK 
952 |0 0  |1 0  |4 0  |6 615_704000000000000_5_Q3  |7 0  |9 119113  |a MGUL  |b MGUL  |c GEN  |d 2017-02-18  |e Calicut Book Distributers Invoice No 10838 dated 18-02-2017  |g 9359.68  |l 0  |o 615.704 5 Q3  |p 56856  |r 2017-04-28  |y BK