Endoglycosidase H

The enzyme '''mannosyl-glycoprotein endo-β-''N''-acetylglucosaminidase (endoglycosidase H)''' () has systematic name ''glycopeptide-D-mannosyl-N⁴-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-β-glucosaminohydrolase''. It is a highly specific endoglycosidase which cleaves asparagine-linked mannose rich oligosaccharides, but not highly processed complex oligosaccharides from glycoproteins. It is used for research purposes to deglycosylate glycoproteins and to monitor intracellular protein trafficking through the secretory pathway. Provided by Wikipedia