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Epigentic technological applications
Epigenetic Technological Applications is a compilation of state-of-the-art technologies involved in epigenetic research. Epigenetics is an exciting new field of biology research, and many technologies are invented and developed specifically for epigenetics study. With chapters covering the latest de...
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| Format: | Printed Book |
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Amsterdam
Elsevier/Academic Press
2015
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| Series: | Translational epigenetics series.
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Table of Contents:
- 1. The State of the Art of Epigenetic Technologies 2. Technologies for the Measurement and Mapping of Genomic 5-Methylcytosine and 5-Hydroxymethylcytosine 3. High-Throughput Sequencing-Based Mapping of Cytosine Modifications 4. Application of Mass Spectrometry in Translational Epigenetics 5. Techniques Analyzing Chromatin Modifications at Specific Single Loci 6. Comprehensive Analysis of Mammalian Linker-Histone Variants and Their Mutants 7. Crystallography-Based Mechanistic Insights into Epigenetic Regulation 8. Chemical and Genetic Approaches to Study Histone Modifications 9. Peptide Microarrays for Profiling of Epigenetic Targets 10. Current Methods for Methylome Profiling 11. Bioinformatics and Biostatistics in Mining Epigenetic Disease Markers and Targets 12. Computational Modeling to Elucidate Molecular Mechanisms of Epigenetic Memory 13. DNA Methyltransferase Inhibitors for Cancer Therapy 14. Histone Acetyltransferases: Enzymes, Assays, and Inhibitors 15. In Vitro Histone Deacetylase Activity Screening: Making a Case for Better Assays 16. Enzymatic Assays of Histone Methyltransferase Enzymes 17. Histone Methyltransferase Inhibitors for Cancer Therapy 18. Discovery of Histone Demethylase Inhibitors 19. Histone Demethylases: Background, Purification, and Detection 20. Animal Model Study of Epigenetic Inhibitors