Loading...

Dynamic Systems Biology Modeling and Simulation

Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems - from molecular/cellular, organ-system, on up to population levels. The book pedagogy is devel...

Full description

Bibliographic Details
Main Author: Joseph J DiStefano, III
Format: Printed Book
Published: Amsterdam Elsevier, Academic Press 2013
Subjects:
Table of Contents:
  • Biosystem modeling and simulation : nomenclature and philosophy
  • Math models of systems : biomodeling 101
  • Computer simulation methods
  • Structural biomodeling from theory and data : compartmentalizations
  • Structural biomodeling from theory and data : sizing, distinguishing and simplifying multicompartmental models
  • Nonlinear mass action and biochemical kinetic interaction modeling
  • Cellular systems biology modeling : deterministic and stochastic
  • Physiologically based, whole-organism kinetics and noncompartmental modeling
  • Biosystem stability and oscillations
  • Structural identifiability
  • Parameter sensitivity methods
  • Parameter estimation and numerical identifiability
  • Parameter estimation methods II : facilitating, simplifying and working with data
  • Biocontrol system modeling, simulation, and analysis
  • Data-driven modeling and alternative hypothesis testing
  • Experiment design and optimization
  • Model reduction and network inference in dynamic systems biology.