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Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery and Development

Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar e...

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Bibliografske podrobnosti
Glavni avtor: Jae S Lee [ editor ]
Drugi avtorji: R Scott Obach; Michael B Fisher
Format: Printed Book
Izdano: CRC Press / Taylor & Francis 2003
Izdaja:Special Indian Edition
Teme:
Opis
Izvleček:Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar enzymes - as well as parallel issues shaping the pharmaceutical industry - to promote the next generation of safer, more effective drugs.
Fizični opis:xx, 588 p. : ill ; 25 cm
ISBN:0824742931