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Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook and Computer Simulations
With its clear, straightforward presentation, this text enables you to grasp all the fundamental concepts of pharmacokinetics and pharmacodynamics. This will allow you to understand the time course of drug response and dosing regimen design.
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| Format: | Printed Book |
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New Jersey
John Wiley & Sons
2011
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Table of Contents:
- Introduction to pharmacokinetics and pharmacodynamics
- Passage of drug through membranes
- Drug absorption
- Drug elimination
- Compartmental models
- Pharmacokinetics of an intravenous bolus injection in a one compartment model
- An intravenous bolus injection in the two compartment model
- Pharmacokinetics of extravascular drug administration
- Introduction to non-compartmental analysis
- Pharmacokinetics of the intravenous infusion in a one compartment model
- Multiple intravenous bolus injections in the one compartment model
- Multiple intermittent infusions
- Multiple oral doses
- Nonlinear pharmacokinetics
- Introduction to pharmacodynamic models and integrated pharmacokinetic- pharmacodynamics (PK-PD) models
- Mechanism based integrated pharmacokinetic-pharmacodynamic models.