Loading...
Lead Generation Approaches in Drug Discovery
An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to imp...
| Hovedforfatter: | |
|---|---|
| Andre forfattere: | |
| Format: | Printed Book |
| Udgivet: |
Hoboken, N.J
John Wiley
2010
|
| Fag: |
Indholdsfortegnelse:
- Lead discovery : the process / William F. Michne
- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy
- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath
- Fragment-based lead discovery / Jeffrey S. Albert
- Design of multitarget ligands / Richard Morphy and Zoran Rankovic
- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak
- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann
- Early screening for ADMET properties / Dennis A. Smith
- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm.