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An Introduction to Systems biology: Design Principles of Biological Circuits

Publisher-supplied data] This book presents recently discovered design principles that govern the structure and behavior of biological networks such as gene circuits, highlighting simple, recurring circuit elements that make up the network. It provides a quantitative theory for which circuits are fo...

Полное описание

Библиографические подробности
Главный автор: Uri Alon
Формат: Printed Book
Опубликовано: Boca Raton, FL Chapman & Hall/CRC 2007
Серии:Chapman and Hall/CRC mathematical & computational biology series, 10.
Предметы:
Оглавление:
  • Ch. 1. Introduction
  • Ch. 2. Transcription networks : basic concepts
  • Ch. 3. Autoregulation : a network motif
  • Ch. 4. The feed-forward loop network motif
  • Ch. 5. Temporal programs and the global structure of transcription networks
  • Ch. 6. Network motifs in developmental, signal transduction, and neuronal networks
  • Ch. 7. Robustness of protein circuits : the example of bacterial chemotaxis
  • Ch. 8. Robust patterning in development
  • Ch. 9. Kinetic proofreading
  • Ch. 10. Optimal gene circuit design
  • Ch. 11. Demand rules for gene regulation
  • Ch. 12. Epilogue : simplicity in biology.