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Computational Systems Bioinformatics: Methods and Biomedical Applications
Computational systems biology (CSB) is a field of research concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. This b...
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World Scientific
2008
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Table of Contents:
- Mathematical, statistical, and data mining principles
- Missing value estimation using KNN and Bayesian methods
- Normalization, scaling, and discretization
- Cross-platform comparison
- Discovering differential biomarkers
- Gene selection and classification
- Gene clustering
- Gene prediction. Reverse engineering : gene regulatory network construction and its behavior
- Motif detection and transcription factor binding site (TFBS) identification
- Gene interaction based on combined microarray and sequence technology
- Protein structure informatics
- Biomarker discovery from proteomics
- Bio-imaging informatics.