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Textbook of Drug Design and Discovery
Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine.The boo...
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| Diğer Yazarlar: | |
| Materyal Türü: | Printed Book |
| Baskı/Yayın Bilgisi: |
London ; New York
Taylor & Francis
2002
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| Edisyon: | 3rd ed |
| Konular: |
| LEADER | 02989nam a2200193Ia 4500 | ||
|---|---|---|---|
| 999 | |c 27100 |d 27100 | ||
| 020 | |a 0415282888 | ||
| 082 | |a 615.1 TEX | ||
| 100 | |a Povl Krogsgaard-Larsen | ||
| 245 | |a Textbook of Drug Design and Discovery | ||
| 250 | |a 3rd ed | ||
| 260 | |a London ; New York |b Taylor & Francis |c 2002 | ||
| 300 | |a xviii, 572 pages : illustrations (some color) ; 25 cm | ||
| 505 | |a Drug design and discovery: an overview / Lester A. Mitscher -- Role of molecular recognition in drug design / Peter Andrews and Michael Dooley -- Stereochemistry in drug design / Ian J. Kennedy and David E. Jane -- Computer-aided development and use of three-dimensional pharmacophore models / Tommy Liljefors and Ingrid Pettersson -- Quantitative structure-activity relationships and experimental design / Ulf Norinder and Thomas Högberg -- Receptors: structure, function and pharmacology / Hans Bräuner-Osborne -- Ion channels: structure, function and pharmacology / David J. Triggle -- Radiotracers: synthesis and use in imaging / Christer Halldin and Thomas Högberg -- Excitatory and inhibitory amino acid receptor ligands / Ulf Madsen and Bente Frølund -- Acetylcholine and histamine receptors and receptor ligands: medicinal chemistry and therapeutic aspects / Povl Krogsgaard-Larsen and Karla Frydenvang -- Dopamine and serotonin receptor and transporter ligands / Klaus P. Bøgesø and Benny Bang-Andersen -- Enzymes and enzyme inhibitors / Robert A. Copeland and Paul S. Anderson -- Metals in medicine: inorganic medicinal chemistry / Ole Farver -- Design and application of prodrugs / Claus S. Larsen and Jesper Østergaard -- Peptides and peptidomimetics / Kristina Luthman and Uli Hacksell -- Classical antiviral agents and design of new antiviral agents / Piet Herdewijn and Erik de Clercq -- Anticancer agents / Ingrid Kjøller Larsen and Jette Sandholm Kastrup. | ||
| 520 | |a Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine.The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included. | ||
| 650 | |a Drug Design. Drug Discovery. | ||
| 700 | |a Tommy Liljefors; Ulf Madsen | ||
| 942 | |c BK | ||
| 952 | |0 0 |1 0 |4 0 |6 615_000000000000000__1_TEX |7 0 |9 29677 |a DCB |b DCB |d 2015-09-01 |l 2 |o 615/.1 TEX |p DCB480 |r 2017-12-11 |s 2017-10-23 |w 2015-09-01 |y BK | ||