טוען...
Post-translational modification of protein biopharmaceuticals /
מחברים אחרים: | |
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פורמט: | Printed Book |
שפה: | English |
יצא לאור: |
Weinheim :
Wiley,
2009.
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נושאים: |
תוכן הענינים:
- Post-translational modification in the context of therapeutic proteins--Glycosylation--Protein glycosylation--Mammalian cell lines and glycosylation--Antibody glycosylation--Gonadotropins and the importance of glycosylation--Yeast glycosylation and engineering in the context of therapeutic proteins--Insect cell glycosylation patterns in the context of biopharmaceuticals--Getting bacteria to glycosylate--Other modifications--Biopharmaceuticals--C-terminal a-amidation--Disulfide bond formation--Engineering of PTMS--Glycoengineering of erythropoietin--Glycoengineering--Engineering in a PTM.