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Post-translational modification of protein biopharmaceuticals /

מידע ביבליוגרפי
מחברים אחרים: Walsh, Gary (Editor)
פורמט: Printed Book
שפה:English
יצא לאור: Weinheim : Wiley, 2009.
נושאים:
תוכן הענינים:
  • Post-translational modification in the context of therapeutic proteins--Glycosylation--Protein glycosylation--Mammalian cell lines and glycosylation--Antibody glycosylation--Gonadotropins and the importance of glycosylation--Yeast glycosylation and engineering in the context of therapeutic proteins--Insect cell glycosylation patterns in the context of biopharmaceuticals--Getting bacteria to glycosylate--Other modifications--Biopharmaceuticals--C-terminal a-amidation--Disulfide bond formation--Engineering of PTMS--Glycoengineering of erythropoietin--Glycoengineering--Engineering in a PTM.