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RNA interference : application to drug discovery and challenges to pharmaceutical development /

"RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of...

תיאור מלא

מידע ביבליוגרפי
מחברים אחרים: Johnson, Paul H.
פורמט: Printed Book
שפה:English
יצא לאור: Hoboken, N.J. : Wiley, c2011.
נושאים:
תוכן הענינים:
  • (Publisher-supplied data) RNA interference: What is it? / James A. Birchler
  • Nucleic acids as regulatory molecules / Faqing Huang, CJ Yu, and Yanlin Guo
  • Use of siRNA oligonucleotides to study gene function / Kristin A. Wiederholt and Adam N. Harris
  • Genome scanning by RNA interference / Roderick L. Beijersbergen and Oliver C. Steinbach
  • Discovery of new siRNA delivery agents / Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay
  • In vivo Delivery of siRNA: challenges and strategies / Aliasger K. Salem and Mark A. Behlke
  • Interferon, cytokine induction and other potential in vivo toxicities / Adam Judge, Marjorie Robbins, and Ian MacLachlan
  • Application of RNA interference to viral diseases / Ralph A. Tripp and Stephen Mark Tompkins.