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RNA interference : application to drug discovery and challenges to pharmaceutical development /
"RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of...
| Údair Eile: | |
|---|---|
| Formáid: | Printed Book |
| Teanga: | English |
| Foilsithe: |
Hoboken, N.J. :
Wiley,
c2011.
|
| Ábhair: |
| LEADER | 02568cam a22003494a 4500 | ||
|---|---|---|---|
| 008 | 100804s2011 njua b 001 0 eng | ||
| 010 | |a 2010030999 | ||
| 016 | 7 | |a 101537510 |2 DNLM | |
| 020 | |a 9780471771517 (cloth) | ||
| 020 | |a 0471771511 (cloth) | ||
| 035 | |a (OCoLC)ocn655301727 | ||
| 042 | |a pcc | ||
| 060 | 0 | 0 | |a 2011 D-062 |
| 060 | 1 | 0 | |a QU 475 |
| 082 | 0 | 0 | |a 572.88 |2 22 |
| 245 | 0 | 0 | |a RNA interference : |b application to drug discovery and challenges to pharmaceutical development / |c edited by Paul H. Johnson. |
| 260 | |a Hoboken, N.J. : |b Wiley, |c c2011. | ||
| 300 | |a xiv, 310 p. : |b ill. ; |c 25 cm. | ||
| 650 | 0 | |a RNA. | |
| 650 | 0 | |a Small interfering RNA. | |
| 650 | 0 | |a Drug development. | |
| 650 | 1 | 2 | |a RNA Interference. |
| 650 | 2 | 2 | |a Drug Discovery. |
| 700 | 1 | |a Johnson, Paul H., | |
| 942 | |c REF | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 8 | |a (Publisher-supplied data) RNA interference: What is it? / James A. Birchler -- Nucleic acids as regulatory molecules / Faqing Huang, CJ Yu, and Yanlin Guo -- Use of siRNA oligonucleotides to study gene function / Kristin A. Wiederholt and Adam N. Harris -- Genome scanning by RNA interference / Roderick L. Beijersbergen and Oliver C. Steinbach -- Discovery of new siRNA delivery agents / Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay -- In vivo Delivery of siRNA: challenges and strategies / Aliasger K. Salem and Mark A. Behlke -- Interferon, cytokine induction and other potential in vivo toxicities / Adam Judge, Marjorie Robbins, and Ian MacLachlan -- Application of RNA interference to viral diseases / Ralph A. Tripp and Stephen Mark Tompkins. | |
| 520 | |a "RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects"--Provided by publisher. | ||
| 906 | |a 7 |b cbc |c orignew |d 1 |e ecip |f 20 |g y-gencatlg | ||
| 955 | |b xh11 2010-08-06 |a rh07 2011-05-26 1 copy rec'd., to CIP ver. | ||
| 999 | |c 96245 |d 96245 | ||
| 952 | |0 0 |1 0 |4 0 |6 572_880000000000000_JOH_R |7 0 |9 96053 |a UL |b UL |c REF |d 2011-11-25 |g 0.00 |l 0 |o 572.88 JOH/R |p 86400 |r 2012-10-28 |v 5770.49 |y REF | ||