|
|
|
|
| LEADER |
03473cam a22003854a 4500 |
| 008 |
090410s2009 njuaf b 001 0 eng |
| 010 |
|
|
|a 2009015172
|
| 016 |
7 |
|
|a 101501869
|2 DNLM
|
| 020 |
|
|
|a 9780470278291 (cloth)
|
| 020 |
|
|
|a 0470278293 (cloth)
|
| 035 |
|
|
|a (OCoLC)ocn319064223
|
| 042 |
|
|
|a pcc
|
| 082 |
0 |
0 |
|a 615/.798
|2 22
|
| 245 |
0 |
0 |
|a Kinase inhibitor drugs /
|c edited by Rongshi Li, Jeffrey A. Stafford.
|
| 260 |
|
|
|a Hoboken, N.J. :
|b Wiley,
|c c2009.
|
| 300 |
|
|
|a xv, 510 p., [16] p. of plates :
|b ill. (some col.) ;
|c 25 cm.
|
| 490 |
1 |
|
|a Wiley series in drug discovery and development
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 505 |
0 |
|
|a The discovery and development of sunitinib (SU11248) : a multitarget tyrosine kinase inhibitor of tumor growth, survival, and angiogenesis / Connie L. Sun, James G. Christensen, and Gerald McMahon -- Tykerb discovery : a dual EGFR and ERBB2 tyrosine kinase inhibitor / Karen Lackey and G. Stuart Cockerill -- Discovery of pazopanib : a pan vascular endothelial growth factor kinase inhibitor / Philip A. Harris and Jeffrey A. Stafford -- The road to ABT-869 : a multitargeted receptor tyrosine kinase inhibitor / Michael Michaelides and Daniel H. Albert -- Discovery of motesanib / Andrew S. Tasker and Vinod F. Patel -- Discovery of brivanib alaninate : a dual vascular endothelial growth factor and fibroblast growth factor receptor inhibitor / Rajeev S. Bhide and Joseph Fargnoli -- Structure-based design and characterization of axitinib / Robert S. Kania -- The road to PD0325901 and beyond : the MEK inhibitors quest / Judith S. Sebolt-Leopold and Alexander J. Bridges -- Discovery of allosteric MEK inhibitors / Eli Wallace and James F. Blake -- Discovery of MK-0457 (VX-680) / Julian M.C. Golec -- Discovery of PHA-739358 / Daniele Fancelli and Jürgen Moll -- Discovery of AZD1152 : a selective inhibitor of aurora-B kinase with potent antitumor activity / Kevin M. Foote and Andrew A. Mortlock -- Case study of aurora-A inhibitor MLN8054 / Christopher F. Claiborne and Mark G. Manfredi -- Discovery of GSK461364 : a polo-like kinase 1 inhibitor for the treatment of cancer / Kevin W. Kuntz and Kyle A. Emmitte -- Pharmacogenomics of dasatinib (Sprycel) / Fei Huang and Edwin A. Clark -- Practical use of computational chemistry in kinase drug discovery / James M. Veal -- Approaches to kinase homology modeling : successes and consideration for the structural kinome / Victoria A. Feher and J. David Lawson -- Fragment-based drug discovery of kinase inhibitors / Daniel A. Erlanson -- Protein kinase structural biology : methods and strategies for targeted drug discovery / Clifford D. Mol, Kengo Okada, and David J. Hosfield.
|
| 650 |
|
0 |
|a Protein kinases
|
| 650 |
|
0 |
|a Antineoplastic agents.
|
| 650 |
1 |
2 |
|a Neoplasms
|
| 650 |
1 |
2 |
|a Protein Kinase Inhibitors
|
| 650 |
2 |
2 |
|a Antineoplastic Agents
|
| 650 |
2 |
2 |
|a Drug Discovery.
|
| 650 |
2 |
2 |
|a Protein Kinase Inhibitors
|
| 650 |
2 |
2 |
|a Protein Kinases
|
| 700 |
1 |
|
|a Li, Rongshi,
|
| 700 |
1 |
|
|a Stafford, Jeffrey A.
|
| 942 |
|
|
|c REF
|
| 830 |
|
0 |
|a Wiley series in drug discovery and development.
|
| 906 |
|
|
|a 7
|b cbc
|c orignew
|d 1
|e ecip
|f 20
|g y-gencatlg
|
| 955 |
|
|
|a xh03 2009-04-21
|a rd13 2009-04-21
|a xe09 2010-03-05 1 copy rec'd., to CIP ver.
|a rg07 2010-05-24 discard (telework)
|
| 999 |
|
|
|c 96224
|d 96224
|
| 952 |
|
|
|0 0
|1 0
|4 0
|6 615_798000000000000_KIN
|7 0
|9 96034
|a UL
|b UL
|c REF
|d 2011-11-25
|g 0.00
|l 0
|o 615.798 KIN
|p 86379
|r 2012-10-28
|v 6623.89
|y REF
|