Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology /

Chi tiết về thư mục
Tác giả khác: Han, Chao, Davis, Charles B., Wang, Binghe
Định dạng: Printed Book
Ngôn ngữ:English
Được phát hành: Hoboken, N.J. : John Wiley & Sons, c2010.
Loạt:Wiley series in drug discovery and development
Những chủ đề:
Drug development.
Pharmacokinetics.
Drugs
Drug Evaluation, Preclinical.
Pharmaceutical Preparations
Pharmacology
Mục lục:
  • Pharmacokinetics in preclinical drug development : an overview / Dion Brocks
  • The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You
  • Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke
  • The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan
  • Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani
  • Prediction of the pharmacokinetics in humans / Chao Han and Ramesh Bambal
  • Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki
  • Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, and Bruce D. Car
  • Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown.

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