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Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology /
| Other Authors: | , , |
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| Format: | Printed Book |
| Language: | English |
| Published: |
Hoboken, N.J. :
John Wiley & Sons,
c2010.
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| Series: | Wiley series in drug discovery and development
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| Subjects: |
Table of Contents:
- Pharmacokinetics in preclinical drug development : an overview / Dion Brocks
- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You
- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke
- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan
- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani
- Prediction of the pharmacokinetics in humans / Chao Han and Ramesh Bambal
- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki
- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, and Bruce D. Car
- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown.