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02400cam a22003734a 4500 |
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090827s2010 njuaf b 001 0 eng |
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|a 2009035876
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7 |
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|a 101514041
|2 DNLM
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|a 9780470044919 (cloth)
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|a (OCoLC)ocn435728364
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|a pcc
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|a 2010 C-003
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|a QV 771
|b E917 2010
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|a 615.19
|2 22
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|a Evaluation of drug candidates for preclinical development :
|b pharmacokinetics, metabolism, pharmaceutics, and toxicology /
|c edited by Chao Han, Charles B. Davis, Binghe Wang.
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260 |
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|a Hoboken, N.J. :
|b John Wiley & Sons,
|c c2010.
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300 |
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|a x, 289 p., [2] p. of plates :
|b ill. (some col.) ;
|c 25 cm.
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490 |
0 |
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|a Wiley series in drug discovery and development
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650 |
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0 |
|a Drug development.
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650 |
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0 |
|a Pharmacokinetics.
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650 |
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0 |
|a Drugs
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650 |
1 |
2 |
|a Drug Evaluation, Preclinical.
|
650 |
2 |
2 |
|a Pharmaceutical Preparations
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650 |
2 |
2 |
|a Pharmacology
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700 |
1 |
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|a Han, Chao.
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700 |
1 |
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|a Davis, Charles B.
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700 |
1 |
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|a Wang, Binghe,
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942 |
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|c REF
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504 |
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|a Includes bibliographical references and index.
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505 |
0 |
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|a Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Ramesh Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, and Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown.
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|a 7
|b cbc
|c orignew
|d 1
|e ecip
|f 20
|g y-gencatlg
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955 |
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|a xh00 2009-09-09
|a xe03 2010-03-25 1 copy rec'd., to CIP ver.
|a xh00 2010-03-29 to USPL/STM
|a xh08 (rev.) 2010-06-04
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|c 96219
|d 96219
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|p 86374
|r 2012-10-28
|v 5268.49
|y TXT
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