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Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology /

Bibliographic Details
Other Authors: Han, Chao, Davis, Charles B., Wang, Binghe
Format: Printed Book
Language:English
Published: Hoboken, N.J. : John Wiley & Sons, c2010.
Series:Wiley series in drug discovery and development
Subjects:
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060 0 0 |a 2010 C-003 
060 1 0 |a QV 771  |b E917 2010 
082 0 0 |a 615.19  |2 22 
245 0 0 |a Evaluation of drug candidates for preclinical development :  |b pharmacokinetics, metabolism, pharmaceutics, and toxicology /  |c edited by Chao Han, Charles B. Davis, Binghe Wang. 
260 |a Hoboken, N.J. :  |b John Wiley & Sons,  |c c2010. 
300 |a x, 289 p., [2] p. of plates :  |b ill. (some col.) ;  |c 25 cm. 
490 0 |a Wiley series in drug discovery and development 
650 0 |a Drug development. 
650 0 |a Pharmacokinetics. 
650 0 |a Drugs 
650 1 2 |a Drug Evaluation, Preclinical. 
650 2 2 |a Pharmaceutical Preparations 
650 2 2 |a Pharmacology 
700 1 |a Han, Chao. 
700 1 |a Davis, Charles B. 
700 1 |a Wang, Binghe, 
942 |c REF 
504 |a Includes bibliographical references and index. 
505 0 |a Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Ramesh Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, and Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown. 
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