LEADER 03150cam a22003734a 4500
008 070427s2007 njua b 001 0 eng
010 |a  2007017891 
016 7 |a 101305787  |2 DNLM 
020 |a 9780471752158 (cloth) 
020 |a 0471752150 (cloth) 
035 |a (OCoLC)ocn123962939 
035 |a (OCoLC)123962939 
042 |a pcc 
060 1 0 |a QV 744  |b A784 2007 
082 0 0 |a 615.19  |2 22 
245 0 4 |a The art of drug synthesis /  |c edited by Douglas S. Johnson, Jie Jack Li. 
260 |a Hoboken, N.J. :  |b Wiley-Interscience,  |c c2007. 
300 |a xv, 276 p. :  |b ill. ;  |c 26 cm. 
504 |a Includes bibliographical references and index. 
505 0 |a The role of medicinal chemistry in drug discovery / John A. Lowe III -- Process research: how much? how soon? / Neal G. Anderson -- Aromatase inhibitors for breast cancer : exemestane (Aromasin), anastrozole (Arimidex), and letrozole (Femara) / Jie Jack Li -- Quinolone antibiotics : levofloxacin (Levaquin), moxifloxacin (Avelox), gemifloxacin (Factive), and garenoxacin (T-3811) / Chris Limberakis -- Triazole antifungals : itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), and fosfluconazole (Prodif) / Andrew S. Bell -- Non-nucleoside HIV reverse transcriptase inhibitors / Arthur Harms -- Neuraminidase inhibitors for influenza : oseltamivir phosphate (Tamiflu) and zanamivir (Relenza) / Douglas S. Johnson and Jie Jack Li -- Peroxisome proliferator-activated receptor (PPAR) agonists for type 2 diabetes / Jin Li -- Angiotensin AT1 antagonists for hypertension / Larry Yet -- Leading ACE inhibitors for hypertension / Victor J. Cee and Edward J. Olhava -- Dihydropyridine calcium channel blockers for hypertension / Daniel P. Christen -- Second-generation HMG-CoA reductase inhibitors / Jeffrey A. Pfefferkorn -- Cholesterol absorption inhibitors: ezetimibe (zetia) / Stuart B. Rosenblum -- Dual selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) for depression / Marta Piñeiro-Núñez -- GABA receptor agonists for insomnia : zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Estorra, Lunesta), and indiplon / Peter R. Guzzo -- Ligands: neurontin (Gabapentin) and lyrica (Pregabalin) / Po-Wai Yuen -- Approved treatments for attention deficit hyperactivity disorder : amphetamine (Adderall), methylphenidate (Ritalin), and atomoxetine (Straterra) / David L. Gray. 
650 0 |a Drugs  |x Design. 
650 0 |a Pharmaceutical chemistry. 
650 1 2 |a Drug Design. 
650 2 2 |a Chemistry, Pharmaceutical  |x methods. 
700 1 |a Johnson, Douglas S. 
700 1 |a Li, Jie Jack. 
856 4 1 |u http://www.loc.gov/catdir/toc/ecip0717/2007017891.html 
856 4 2 |u http://www.loc.gov/catdir/enhancements/fy0739/2007017891-b.html 
856 4 2 |u http://www.loc.gov/catdir/enhancements/fy0739/2007017891-d.html 
942 |c BK 
906 |a 7  |b cbc  |c orignew  |d 1  |e ecip  |f 20  |g y-gencatlg 
955 |a aa27 2007-05-09  |a ps08 2007-08-16 1 copy rec'd., to CIP ver.  |a xf04 2009-02-04 copy 2 added 
999 |c 95967  |d 95967 
952 |0 0  |1 0  |4 0  |6 615_190000000000000_JOH_A  |7 0  |9 95844  |a UL  |b UL  |c ST1  |d 2011-11-14  |g 0.00  |l 0  |o 615.19 JOH/A  |p 86104  |r 2012-10-28  |v 5820.69  |y BK