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Family matters : designing, analysing, and understanding family-based studies in life course epidemiology /
Family-based studies, including intergenerational, sibling, and twin studies, are increasingly being used to explore life course epidemiology. However, there are issues relating to study design and the statistical analysis of family-based studies that are still not well understood, and comprehending...
| Other Authors: | , |
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| Format: | Printed Book |
| Language: | English |
| Published: |
Oxford ; New York :
Oxford University Press,
C2009.
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| Subjects: |
| LEADER | 04053cam a22004217a 4500 | ||
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| 010 | |a 2009288494 | ||
| 015 | |a GBA8D6221 |2 bnb | ||
| 016 | 7 | |a 101505913 |2 DNLM | |
| 016 | 7 | |a 014844625 |2 Uk | |
| 020 | |a 9780199231034 (pbk.) | ||
| 020 | |a 0199231036 (pbk.) | ||
| 035 | |a (OCoLC)ocn277068139 | ||
| 042 | |a nlmcopyc |a lccopycat | ||
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| 060 | 1 | 0 | |a QZ 50 |b F198 2009 |
| 082 | 0 | 4 | |a 614.4 |2 22 |
| 245 | 0 | 0 | |a Family matters : |b designing, analysing, and understanding family-based studies in life course epidemiology / |c edited by Debbie A. Lawlor, Gita D. Mishra. |
| 260 | |a Oxford ; |a New York : |b Oxford University Press, |c C2009. | ||
| 300 | |a x, 341 p. : |b ill. ; |c 25 cm. | ||
| 500 | |a Fourth book in the extremely successful Life Course Approach to Adult Health series Details underlying assumptions of family-based studies, to assist the reader in interpreting their findings Describes how doing studies within families can help us to understand whether a risk factor is causal or not, without having to do experiments with humans Describes the practicalities of doing these family-based studies, some of the pitfalls, and how to avoid them Describes practical difficulties of establishing and running a birth cohort in both high-income and low-middle income countries, and ways to minimise them Provides statistical formulae and programming syntax Contains examples of uses of family-based studies, including how they have helped understanding of the causes of disease, which also assists in understanding the limitations of such studies | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a Family-based studies, including intergenerational, sibling, and twin studies, are increasingly being used to explore life course epidemiology. However, there are issues relating to study design and the statistical analysis of family-based studies that are still not well understood, and comprehending the underlying assumptions of these studies and drawing the inferences from them can be complex. This book provides the knowledge and skills required to design, analyse, and correctly interpret family-based studies. It explains what these studies can tell us about life course epidemiology; provides practical guidance on how to set-up and maintain birth cohorts for completing family-based studies in life course epidemiology; describes how to undertake appropriate statistical analyses of family-based studies and correctly interpret results from these analyses; and provides examples that illustrate the ways in which family-based studies can enhance our understanding of life course epidemiology. In addition, there is discussion of difficulties specific to setting up such studies in low- and middle-income countries, and issues relating to proxy informants, where parents provide information on children and vice versa, or siblings provide information about each other. Examples of how family-based studies have been used in understanding the life course epidemiology of cardiovascular disease, mental health, and reproductive health illustrate the applicability of the research to these areas, but also more generally to the wider field of life course epidemiology. | ||
| 650 | 0 | |a Public health |x Longitudinal research. | |
| 650 | 0 | |a Epidemiology. | |
| 650 | 0 | |a Families |x Health and hygiene |x Longitudinal research. | |
| 650 | 1 | 2 | |a Disease Susceptibility |x epidemiology. |
| 650 | 1 | 2 | |a Family. |
| 650 | 2 | 2 | |a Longitudinal Studies. |
| 650 | 2 | 2 | |a Research Design. |
| 650 | 2 | 2 | |a Risk Assessment. |
| 700 | 1 | |a Lawlor, Debbie A. | |
| 700 | 1 | |a Mishra, Gita D. | |
| 942 | |2 ddc |c BK | ||
| 906 | |a 7 |b cbc |c copycat |d 2 |e ncip |f 20 |g y-gencatlg | ||
| 955 | |b xh13 2009-09-01 z-processor to STM |a xh00 2009-09-01 to USPL/STM |i xh61 2010-03-05 |a Barcode 00239846142 returned from bindery 2010-04-13 | ||
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