Animal models for the study of human disease /

Bibliographic Details
Other Authors: Conn, P. Michael (Editor)
Format: Printed Book
Language:English
Published: London : Academic Press, c2017.
Edition:Second edition.
Subjects:
Diseases > Animal models.
Laboratory animals.
Pathology, Experimental.
Electronic books.
Online Access:ScienceDirect - Full text online
Table of Contents:
  • Cover; Dedication; Title Page; Copyright Page; Dedication; Contents; List of Contributors; Preface; Part A
  • Ethics, resources, and approaches; Chapter 1
  • Ethics in Biomedical Animal Research: The Key Role of the Investigatora; 1
  • Nature and Scope of the Chapter; 2
  • The Subject Matter of Biomedical Animal Research Ethics; 3
  • Why Investigators Should Care About Biomedical Animal Research Ethics; 3.1
  • Investigators are Already Committed to High Ethical Standards; 3.2
  • Ethical Treatment of Animals is Required by Law; 3.2.1
  • General Commitment to Ethical Behavior
  • 3.2.2
  • Legal Requirements Reflecting General or Specific Ethical Principles3.3
  • Ethical Treatment of Animals Promotes Sound Scientific Results; 3.4
  • Ethical Treatment of Animals is Required by Funding Bodies; 3.5
  • Ethical Treatment of Animals is Required by Peer-Reviewed Journals; 3.5.1
  • The ARRIVE Guidelines; 3.6
  • Ethical Treatment of Animals is Essential for Public Support; 3.7
  • Ethical Treatment of Animals is the Right Thing to Do; 4
  • Aspects of Animal Use and Care Relevant to Biomedical Animal Research Ethics; 5
  • Use of Privately Owned Animals in Biomedical Research
  • 6
  • The Nature of Basic Animal Research6.1
  • "Basic" Research as the Search for Knowledge for its Own Sake; 6.2
  • "Basic" Research as the Search for Fundamental, Underlying Mechanisms, and Causes; 6.3
  • What Investigators Mean by "Basic" Animal Research; 6.4
  • Recommendations; 7
  • Why Investigators Play the Key Role in Ensuring the Ethical Conduct of Animal Research Projects; 7.1
  • The Nature of Principles of Biomedical Animal Research Ethics; 7.2
  • The Need for Scientific Expertise in Applying General Ethical Principles; 7.3
  • The Investigator as Captain of the Experimental Ship
  • 7.3.1
  • Primacy of Project Goals7.3.2
  • Design and Implementation of Experimental Procedures; 7.3.3
  • The Importance of Sound Science in Ensuring Ethical Animal Experimentation; 7.4
  • The Role of Review Committees and Government Officials in Assessing the Ethical Appropriateness of Animal Experiments; 7.4.1
  • Ethical Review in the United States; 8
  • Sources of Guidance for Investigators in Conducting Ethical Research; 8.1
  • Scientific Resources; 8.2
  • Ethical and Ethically Relevant Resources; 8.2.1
  • Legally Mandated Ethical Principles
  • 8.2.2
  • Nongovernmental Documents Adherence to Which is Required by Law8.2.3
  • Publications of Workshops, Study Committees, and Nongovernmental Entities; 8.2.4
  • Ethical Guidelines of Professional Associations; 9
  • Developing Useful Ethical Guidelines; 10
  • Fundamental Principles of biomedical animal Research Ethics; F1
  • The Biomedical Research Principle; F2
  • The Animal Research Principle; F3
  • The Nuremberg Principle; F4
  • The Pain and Distress Minimization Principle; F4.1
  • Ethical Foundations of the Pain and Distress Minimization Principle
  • F4.2
  • Qualifications to the Pain and Distress Minimization Principle

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