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Animal models for the study of human disease /

Dettagli Bibliografici
Altri autori: Conn, P. Michael (Redattore)
Natura: Printed Book
Lingua:English
Pubblicazione: London : Academic Press, c2017.
Edizione:Second edition.
Soggetti:
Accesso online:ScienceDirect - Full text online
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245 0 0 |a Animal models for the study of human disease /  |c edited by P. Michael Conn. 
250 |a Second edition. 
260 |a London :  |b Academic Press,  |c c2017. 
300 |a 1177 p. 
500 |a Includes index. 
505 0 |a Cover; Dedication; Title Page; Copyright Page; Dedication; Contents; List of Contributors; Preface; Part A -- Ethics, resources, and approaches; Chapter 1 -- Ethics in Biomedical Animal Research: The Key Role of the Investigatora; 1 -- Nature and Scope of the Chapter; 2 -- The Subject Matter of Biomedical Animal Research Ethics; 3 -- Why Investigators Should Care About Biomedical Animal Research Ethics; 3.1 -- Investigators are Already Committed to High Ethical Standards; 3.2 -- Ethical Treatment of Animals is Required by Law; 3.2.1 -- General Commitment to Ethical Behavior 
505 8 |a 3.2.2 -- Legal Requirements Reflecting General or Specific Ethical Principles3.3 -- Ethical Treatment of Animals Promotes Sound Scientific Results; 3.4 -- Ethical Treatment of Animals is Required by Funding Bodies; 3.5 -- Ethical Treatment of Animals is Required by Peer-Reviewed Journals; 3.5.1 -- The ARRIVE Guidelines; 3.6 -- Ethical Treatment of Animals is Essential for Public Support; 3.7 -- Ethical Treatment of Animals is the Right Thing to Do; 4 -- Aspects of Animal Use and Care Relevant to Biomedical Animal Research Ethics; 5 -- Use of Privately Owned Animals in Biomedical Research 
505 8 |a 6 -- The Nature of Basic Animal Research6.1 -- "Basic" Research as the Search for Knowledge for its Own Sake; 6.2 -- "Basic" Research as the Search for Fundamental, Underlying Mechanisms, and Causes; 6.3 -- What Investigators Mean by "Basic" Animal Research; 6.4 -- Recommendations; 7 -- Why Investigators Play the Key Role in Ensuring the Ethical Conduct of Animal Research Projects; 7.1 -- The Nature of Principles of Biomedical Animal Research Ethics; 7.2 -- The Need for Scientific Expertise in Applying General Ethical Principles; 7.3 -- The Investigator as Captain of the Experimental Ship 
505 8 |a 7.3.1 -- Primacy of Project Goals7.3.2 -- Design and Implementation of Experimental Procedures; 7.3.3 -- The Importance of Sound Science in Ensuring Ethical Animal Experimentation; 7.4 -- The Role of Review Committees and Government Officials in Assessing the Ethical Appropriateness of Animal Experiments; 7.4.1 -- Ethical Review in the United States; 8 -- Sources of Guidance for Investigators in Conducting Ethical Research; 8.1 -- Scientific Resources; 8.2 -- Ethical and Ethically Relevant Resources; 8.2.1 -- Legally Mandated Ethical Principles 
505 8 |a 8.2.2 -- Nongovernmental Documents Adherence to Which is Required by Law8.2.3 -- Publications of Workshops, Study Committees, and Nongovernmental Entities; 8.2.4 -- Ethical Guidelines of Professional Associations; 9 -- Developing Useful Ethical Guidelines; 10 -- Fundamental Principles of biomedical animal Research Ethics; F1 -- The Biomedical Research Principle; F2 -- The Animal Research Principle; F3 -- The Nuremberg Principle; F4 -- The Pain and Distress Minimization Principle; F4.1 -- Ethical Foundations of the Pain and Distress Minimization Principle 
505 8 |a F4.2 -- Qualifications to the Pain and Distress Minimization Principle 
650 0 |a Diseases  |x Animal models. 
650 0 |a Laboratory animals. 
650 0 |a Pathology, Experimental. 
700 1 |a Conn, P. Michael,  |e editor. 
856 4 0 |3 ScienceDirect - Full text online  |u http://www.library.illinois.edu/proxy/go.php?url=http://www.sciencedirect.com/science/book/9780128094686 
942 |c BK 
655 4 |a Electronic books. 
852 8 |b eresour-nc  |h Online Resource  |t 1  |z Accessible anywhere on campus or with UIUC NetID 
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