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Proteases and cancer methods and protocols /
Proteases decisively contribute to cancer development and promotion by regulating the activities of growth factors/cytokines and signaling receptors, as well as the composition of the extracellular matrix, thereby suppressing cell death pathways and activating cell survival pathways. In Proteases an...
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| Other Authors: | , |
| Format: | Printed Book |
| Language: | English |
| Published: |
New York, N.Y. :
Humana Press,
c2009.
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| Series: | Methods in molecular biology (Clifton, N.J.) ;
v. 539. Springer protocols. |
| Subjects: | |
| Online Access: | SpringerLink - Full Text Online Service |
Table of Contents:
- Delineating protease functions during cancer development / Nesrine I. Affara, Pauline Andreu, and Lisa M. Coussens
- Proteolytic systems : constructing degradomes / Gonzalo R. Ordnez ... [et al.]
- Microarrays for protease detection in tissues and cells / Kamiar Moin ... [et al.]
- Positional scanning synthetic combinatorial libraries for substrate profiling / Eric L. Schneider and Charles S. Craik
- Mixture-based peptide libraries for identifying protease cleavage motifs / Benjamin E. Turk
- High throughput substrate phage display for protease profiling / Boris Ratnikov, Piotr Cieplak, and Jeffrey W. Smith
- Imaging specific cell surface protease activity in living cells using reengineered bacterial cytotoxins / John P. Hobson ... [et al.]
- Cell-based identification of natural substrates and cleavage sites for extracellular proteases by SILAC proteomics / Magda Gioia, Leonard J. Foster, and Christopher M. Overall
- Optical proteolytic beacons for in vivo detection of matrix metalloproteinase activity / J. Oliver McIntyre and Lynn M. Matrisian
- Dissecting the urokinase activation pathway using urokinase-activated anthrax toxin / Shihui Liu ... [et al.]
- On-demand cleavable linkers for radioimmunotherapy / Pappanaicken R. Kumaresan, Juntao Luo and Kit S. Lam.