Loading...

Hematology : Basic principles and practice basic principles and practice /

Bibliographic Details
Main Author: Hoffman,Ronald
Other Authors: Hoffman, Ronald
Format: Printed Book
Published: Philadelphia, PA : Saunders/Elsevier, c2013.
Edition:6th ed.
Subjects:
Table of Contents:
  • Acute myeloid leukemia in children
  • Myelodysplastic and myeloproliferative neoplasms in children
  • Pathobiology of acute lymphoblastic leukemia
  • Clinical manifestations and treatment of acute lymphoblastic leukemia in children
  • Acute lymphoblastic leukemia in adults
  • Chronic myeloid leukemia
  • The polycythemias
  • Essential thrombocythemia
  • Primary myelofibrosis
  • Eosinophilia, eosinophil-associated diseases, chronic eosinophil leukemia, and the hypereosinophilic syndromes
  • Mast cellls and systemic mastocytosis
  • Pathologic basis for the classification of non-hodgkin and hodgkin lymphomas
  • Origin of hodgkin lymphoma
  • Hodgkin lymphoma: clinical manifestations, staging, and therapy
  • Origin of non-Hodgkin lymphoma
  • Chronic lymphocytic leukemia
  • Hairy cell leukemia
  • Clinical manifestations and treatment of marginal zone lymphomas (extranodal/malt, splenic, and nodal)
  • Clinical manifestations, staging, and treatment of follicular lymphoma
  • Mantle cell lymphoma
  • Diagnosis and treatment of diffuse large b-cell lymphoma and Burkitt lymphoma
  • Virus-associated lymphoma
  • Malignant lymphomas in childhood
  • T-cell lymphomas
  • Plasma cell neoplasms
  • Waldenstrèom macroglobulinemia and lymphoplasmacytic lymphoma
  • Immunoglobulin light-chain amyloidosis (primary amyloidosis)
  • Clinical approach to infections in the compromised host
  • Indwelling access devices
  • Nutritional issues in patients with hematologic malignancies
  • Psychosocial aspects of hematologic disorders
  • Pain management and antiemetic therapy in hematologic disorders
  • Palliative care
  • Late complications of hematologic diseases and their therapies
  • Overview and historical perspecitve of current cell-based therapies
  • Practical aspects of hematologic stem cell harvesting and mobilization
  • Preclinical process of cell-based therapies
  • Graft engineering and cell processing
  • Principles of cell-based genetic therapies
  • Mesenchymal stromal cells
  • T-cell therapy of hematologic diseases
  • Natural killer cell-based therapies
  • Dendritic cell therapies
  • Overview of hematopoietic stem cell transplantation
  • Indications and outcome of allogeneic hematopoietic cell transplantation for hematologic malignancies in adults
  • Unrelated donor hematopoietic cell transplantation
  • Haploidentical hematopoietic cell transplantation
  • Unrelated donor cord blood transplantation for hematologic malignancies
  • Graft-versus-host disease and graft-versus-leukemia responses
  • Complications after hematopoietic stem cell transplantation
  • Human blood group antigens and antibodies
  • Principles of red blood cell transfusion
  • Principles of platelet transfusion therapy
  • Human leukocyte antigen and human neutrophil antigen systems
  • Principles of neutrophil (granulocyte) transfusions
  • Principles of plasma transfusion: plasma, cryoprecipitate, albumin, and immunoglobulins
  • Anatomy and physiology of the gene
  • Genomic approaches to hematology
  • Regulation of gene expression, transcription, splicing, and RNA metabolism
  • Protein synthesis, processing, and trafficking
  • Protein architecture: relationship of form and function
  • Signaling transduction and regulation of cell metabolism
  • Pharmacogenomics and hematologic diseases
  • Hematopoietic stem cell biology
  • Hematopoietic microenvironment
  • Cell adhesion
  • Hematopoietic cell trafficking and chemokines
  • Dynamic interactions between hematopoietic stem and progenitor cells and the bone marrow: current biology of stem cell homing and mobilization
  • Vascular growth in heatlh and disease
  • Principles of cytokine signaling
  • Control of cell division
  • Cell death
  • Overview and compartmentalization of the immune system
  • B-cell development
  • T-cell immunity
  • Natural killer cell immunity
  • Dendritic cell biology
  • Complement and immunoglobulin biology
  • Tolerance and autoimmunity
  • Biology of erythropoiesis, erythroid differentiation, and maturation
  • Granulocytopoiesis and monocytopoiesis
  • Thrombocytopoiesis
  • Inherited forms of bone marrow failure
  • Aplastic anemia
  • Paroxysmal nocturnal hemoglobinuria
  • Acquried disorders of red cell, white cell, and platelet production
  • Pathobiology of the human erythrocyte and its hemoglobins
  • Approach to anemia in the adult and child
  • Pathophysiology of iron homeostasis
  • Disorders of iron homeostasis: iron deficiency and overload
  • Anemia of chronic diseases
  • Heme biosynthesis and its disorders: porphyrias and sideroblastic anemias
  • Megaloblastic anemias
  • Thalassemia syndromes
  • Pathobiology of sickle cell disease
  • Sickle cell disease: clinical features and management
  • Hemoglobin variants associated with hemolytic anemia, altered oxygen affinity, and methemoglobinemias
  • Red blood cell enzymopathies
  • Red blood cell membrane disorders
  • Autoimmune hemolytic anemia
  • Extrinsic nonimmune hemolytic anemias
  • Neurotrophilic leukocytosis, neurotropenia, monocytosis, and monocytopenia
  • Lymphocytosis, lymphocytopenia, hypergammaglobulinemia, and hypogammaglobulinema
  • Disorders of phagocyte function
  • Congenital disorders of lymphocyte function
  • Histiocytic disorders
  • Lysosomal storage diseases: perspectives and principles
  • Infections mononucleosis and other Epstein-Barr virus-associated diseases
  • Progress in the classification of myeloid neoplasms: clinical implications
  • Conventional and molecular cytogenetic basis of hemotologic malignancies
  • Radiation therapy in the treatment of hematologic malignancies
  • Pathobiology of acute myeloid leukema
  • Clinical mainfestations and treatment of acute myeloid leukemia
  • Myelodysplastic syndromes: biology and treatment
  • Allogenic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome in adults
  • Preparation of plasma-derived and recombinant human plasma proteins
  • Transfusion therapy for coagulation factor deficiencies
  • Hemapheresis
  • Transfusion reactions to blood and cell therapy products
  • Transfusion-transmitted diseases
  • Transfusion medicine in hematopoietic stem cell and solid organ transplantation
  • Pediatric transfusion medicine
  • Overview of hemostasis and thrombosis
  • The blood vessel wall
  • Megakaryocyte and platelet structure
  • Molecular basis for platelet function
  • Molecular basis of blood coagulation
  • Regulatory mechanisms in hemostasis
  • Clinical approach to the patient with bleeding or bruising
  • Laboratory evaluation of hemostatic and thrombotic disorders
  • Acquired disorders of platelet function
  • Diseases of platelet number: immune thrombocytopenia, neonatal alloimmune thrombocytopenia, and posttransfusion purpura
  • Thrombocytopenia caused by platelet destruction, hypersplenism, or hemodilution
  • Heparin-induced thrombocytopenia
  • Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome
  • Hemophilia A and B
  • Inhibitors in hemophilia A and B
  • Rare coagulation factor deficiencies
  • Structure, biology, and genetics of von willebrand factor
  • Disseminated intravascular coagulation
  • Hypercoagulable states - Antiphospholipid syndrome
  • Venous thromboembolism
  • Mechanical interventions in arterial and venous thrombosis
  • Atherothrombosis
  • Stroke
  • Acute coronary syndromes
  • Atrial fibrillation
  • Peripheral artery disease
  • Antithrombotic drugs
  • Disorders of coagulation in the neonate
  • Hematologic changes in pregnancy
  • Hematologic manifestations of childhood illness
  • Hematologic manifestations of liver disease
  • Hematologic manifestations of systemic disease: renal disease
  • Hematologic manifestations of cancer
  • Integrative therapies in patients with hematologic diseases
  • Hematologic manifestations of HIV/AIDS
  • Hematologic aspects of parasitic diseases
  • Hematologic problems in the surgical patient: bleeding and thrombosis
  • The spleen and its disorders
  • Hematology in aging
  • Resources for the hematologist: interpretive comments and selected reference values for neonatal, pediatric, and adult populations.