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Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations /

Bibliographic Details
Main Author: Rosenbaum, Sara
Format: Printed Book
Language:English
Published: Hoboken, N.J. : John Wiley & Sons, c2011.
Subjects:
Table of Contents:
  • Introduction to pharmacokinetics and pharmacodynamics
  • Passage of drug through membranes
  • Drug absorption
  • Drug elimination
  • Compartmental models
  • Pharmacokinetics of an intravenous bolus injection in a one compartment model
  • An intravenous bolus injection in the two compartment model
  • Pharmacokinetics of extravascular drug administration
  • Introduction to non-compartmental analysis
  • Pharmacokinetics of the intravenous infusion in a one compartment model
  • Multiple intravenous bolus injections in the one compartment model
  • Multiple intermittent infusions
  • Multiple oral doses
  • Nonlinear pharmacokinetics
  • Introduction to pharmacodynamic models and integrated pharmacokinetic- pharmacodynamics (PK-PD) models
  • Mechanism based integrated pharmacokinetic-pharmacodynamic models.