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Genes V /
| Main Author: | |
|---|---|
| Format: | Printed Book |
| Language: | English |
| Published: |
Oxford ; New York :
Oxford University Press,
1994.
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| Subjects: |
Table of Contents:
- Cells as macromolecular assemblies
- Cells obey the laws of physics and chemistry
- Cells are organized into compartments
- DNA as a store of information
- Genes are mutable units
- DNA is the genetic material
- Topology of nucleic acids
- Isolating the gene
- Translation: expressing genes as proteins
- Assembly line for protein synthesis
- Transfer RNA is the translational adaptor
- Ribosomes provide a translation factory
- Messenger RNA is the template
- Constructing the cell
- Apparatus for protein localization
- Receptors and signal transduction: channels and ion uptake
- Cell cycle and growth regulation
- Control of prokaryotic gene expression
- Control at initiation: RNA polymerase-promoter interactions
- Panoply of operons: the lactose paradigm and others
- Control by RNA structure: termination and antitermination
- Phage strategies: lytic cascades and lysogenic repression
- Perpetuation of DNA
- Replicon: unit of replication
- Primosomes and replisomes: the apparatus for DNA replication
- Systems that safeguard DNA.
- (cont) Organization of the eukaryotic genome
- Extraordinary power of DNA technology
- Genome size and genetic content
- Eukaryotic gene: conserved exons and unique introns
- Gene numbers: repetition and redundancy
- Genomes sequestered in organelles
- Organization of simple sequence DNA
- Genome is packaged into chromosomes
- Chromosomes consist of nucleosomes
- Eukaryotic transcription and RNA processing
- Building the transcription complex: promoters, factors and RNA polymerases
- Regulation of transcription: factors that activate the basal apparatus
- Apparatus for nuclear splicing
- RNA as catalyst: changing the informational content of RNA
- Dynamic genome: DNA in flux
- Recombination of DNA
- Transposons that mobilize via DNA
- Retroviruses and retroposons
- Rearrangement and amplification in the genome
- Genes in development
- Generation of immune diversity by gene reorganization
- Gene regulation in development: gradients and cascades
- Oncogenes: gene expression and cancer
- Landmark shifts in perspectives.