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02846cam a2200217 a 4500 |
| 008 |
940614s1994 enka b 001 0 eng |
| 020 |
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|a 0198542879
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| 035 |
|
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|a (OCoLC)ocm31331201
|
| 082 |
0 |
0 |
|a 575.1
|2 20
|
| 100 |
1 |
|
|a Lewin, Benjamin.
|
| 245 |
1 |
0 |
|a Genes V /
|c Benjamin Lewin.
|
| 260 |
|
|
|a Oxford ;
|a New York :
|b Oxford University Press,
|c 1994.
|
| 300 |
|
|
|a xxiv, 1272 p. :
|b ill. (some col.) ;
|c 29 cm.
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 505 |
0 |
|
|a Cells as macromolecular assemblies -- Cells obey the laws of physics and chemistry -- Cells are organized into compartments -- DNA as a store of information -- Genes are mutable units -- DNA is the genetic material -- Topology of nucleic acids -- Isolating the gene -- Translation: expressing genes as proteins -- Assembly line for protein synthesis -- Transfer RNA is the translational adaptor -- Ribosomes provide a translation factory -- Messenger RNA is the template -- Constructing the cell -- Apparatus for protein localization -- Receptors and signal transduction: channels and ion uptake -- Cell cycle and growth regulation -- Control of prokaryotic gene expression -- Control at initiation: RNA polymerase-promoter interactions -- Panoply of operons: the lactose paradigm and others -- Control by RNA structure: termination and antitermination -- Phage strategies: lytic cascades and lysogenic repression -- Perpetuation of DNA -- Replicon: unit of replication -- Primosomes and replisomes: the apparatus for DNA replication -- Systems that safeguard DNA.
|
| 505 |
0 |
|
|a (cont) Organization of the eukaryotic genome -- Extraordinary power of DNA technology -- Genome size and genetic content -- Eukaryotic gene: conserved exons and unique introns -- Gene numbers: repetition and redundancy -- Genomes sequestered in organelles -- Organization of simple sequence DNA -- Genome is packaged into chromosomes -- Chromosomes consist of nucleosomes -- Eukaryotic transcription and RNA processing -- Building the transcription complex: promoters, factors and RNA polymerases -- Regulation of transcription: factors that activate the basal apparatus -- Apparatus for nuclear splicing -- RNA as catalyst: changing the informational content of RNA -- Dynamic genome: DNA in flux -- Recombination of DNA -- Transposons that mobilize via DNA -- Retroviruses and retroposons -- Rearrangement and amplification in the genome -- Genes in development -- Generation of immune diversity by gene reorganization -- Gene regulation in development: gradients and cascades -- Oncogenes: gene expression and cancer -- Landmark shifts in perspectives.
|
| 650 |
|
0 |
|a Genetics
|
| 740 |
0 |
1 |
|a Genes five.
|
| 942 |
|
|
|c BK
|
| 999 |
|
|
|c 150978
|d 150978
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| 952 |
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|s 2013-11-28
|w 2018-08-10
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