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Essential developmental biology /
| Main Author: | |
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| Format: | Printed Book |
| Language: | English |
| Published: |
Malden, MA : Abingdon, Oxon :
Blackwell Science : Distributors Marston Book Services,
2001.
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| Subjects: | |
| Online Access: | Table of contents Contributor biographical information Publisher description |
Table of Contents:
- Machine generated contents note: Section 1: Groundwork, 1
- 1 The Excitement of Developmental Biology, 3
- Where the subject came from, 3
- Central position in biology, 3
- Impact on society, 4
- Future impact, 4
- 2 General Problems of Development, 6
- Nuclear totipotency, cloning of animals, 7
- 3 Key Molecular Components, 10
- Genes, 10
- Signalling systems, 13
- Cytoskeleton, 16
- Cell adhesion molecules, 18
- Appendix,19
- Transcription factor families, 19
- Inducing factor families, 20
- Cell adhesion molecules, 24
- Extracellular matrix components, 25
- 4 Common Features of Development, 27
- Gametogenesis, 27
- Fertilization, 30
- Early development, 30
- Morphogenetic processes, 35
- Evolution of developmental mechanisms,41
- 5 Developmental Genetics, 48
- Developmental mutants, 48
- Screening for mutants, 53
- Cloning of genes, 55
- Transgenesis, 55
- Limitations of developmental genetics, 57
- 6 Experimental Embryology, 60
- Normal development, 60
- Developmental commitment, 63
- Acquisition of commitment, 66
- Homeotic genes, 68
- 7 Techniques for the Study of Development, 73
- Microscopy, 73
- Study of gene expression by biochemical methods, 76
- In situ methods, 79
- Microinjection, 81
- Cell-labelling methods, 83
- Reporter genes, 84
- Section 2: Major Model Organisms, 87
- 8 Model Organisms, 89
- Availability and cost, 89
- Access and micromanipulation, 90
- Genetics and genome maps, 90
- Relevance, 91
- 9 Xenopus,93
- Oogenesis, maturation, fertilization, 93
- Embryonic development, 94
- Experimental methods, 100
- Regional specification, 103
- Inductive interactions, 108
- 10 TheZebrafish, 116
- Normal development, 116
- Mutagenesis, 117
- Regional specification, 120
- 11 The Chick, 122
- Normal development, 123
- Regional specification of the early embryo, 129
- Description of organogenesis in the chick, 131
- 12 The Mouse, 140
- Normal development, 140
- Technology of mouse development, 149
- Regional specification in development, 158
- Other topics in mouse development, 162
- 13 Drosophila,165
- Insects, 165
- Normal development, 166
- Drosophila developmental genetics, 169
- Overview of the developmental program, 173
- The dorsoventral pattern, 174
- The anteroposterior system, 178
- 14 Caenorhabditis elegans, 191
- Normal development, 191
- Regional specification in the embryo, 193
- Analysis of postembryonic development, 198
- Programmed cell death, 200
- Section 3: Organogenesis and Regeneration, 205
- 15 Tissues, 207
- Epithelial tissues, 207
- Connective tissues, 207
- Muscle, 209
- Neural tissues, 209
- Blood and blood vessels, 209
- 16 Development of the Nervous System, 212
- Overall structure and cell types, 212
- Anteroposterior patterning of the neural plate, 216
- Dorsoventral patterning of the neural tube, 219
- Neurogenesis and gliogenesis, 220
- The neural crest, 224
- Development of neuronal connectivity 227
- 17 Development of Mesodermal Organs, 236
- Somitogenesis, 236
- The kidney, 242
- Gonadal development, 245
- Limb development, 250
- 18 Drosophila Imaginal Discs, 262
- Metamorphosis, 262
- Genetic study of larval development, 262
- Mitotic recombination, 264
- Disc development, 268
- Regional patterning of the wing disc, 272
- Regional patterning of the leg disc, 275
- 19 Stem Cells and Tissue Growth, 278
- Size and proportion, 278
- Renewal tissues, 279
- Growth in stature, 288
- Postnatal disorders of growth and differentiation, 291
- Cancer, 291
- 20 Regeneration of Missing Parts, 296
- Distribution of regenerative capacity, 296
- Planarian regeneration, 297
- Vertebrate limb regeneration, 300.