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Clinical biochemistry /
| Main Author: | |
|---|---|
| Format: | Printed Book |
| Language: | English |
| Published: |
New Delhi :
Viva Books,
c2010.
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| Edition: | 2nd ed. |
| Subjects: |
Table of Contents:
- Clinical biochemistry - What is clinical biochemistry? - The role of the clinical biochemistry laboratory - What does the result mean? - Reference ranges - Clinical utility - Blood samples - Units of measurement - Suggested further reading - Self-assessment questions - Input - Nutrition and drugs - Composition of the body - Macronutrients - Micronutrients - Minerals and trace elements - Assessment of nutritional status - Toxicology - Laboratory measurement of nutrients and drugs - Spectroscopy and colorimetry - Suggested further reading - Self-assessment questions - Digestion - The food we eat - The digestive process - Gut hormones - Clinical disorders - Investigation of malabsorption - Suggested further reading - Self-assessment questions - Control - Genetic control - DNA and genetic information - Proteins from DNA - Genetic damage - Cancer and tumour markers - Genetic disease and the clinical biochemistry laboratory - Suggested further reading - Self-assessment questions - Endocrinology - chemical control - Transport of hormones - Action of hormones - Control of hormone production - The hypothalamic-pituitary axis - Endocrine disorders - Investigation of endocrine disease - Measurement of hormones - Suggested further reading - Self-assessment questions - Thyroid hormones - The thyroid gland - Thyroid hormones - Action of thyroid hormones - Thyroid hormone homeostasis - Thyroid disease - Measurement of thyroid hormones - Suggested further reading - Self-assessment questions - Control of water and electrolyte metabolism - Water balance - The importance of sodium - Control of osmolality - Disorders of water and electrolyte balance - Potassium - Disorders of potassium metabolism - Measurement of sodium and potassium - Suggested further reading - Self-assessment questions - Control of calcium metabolism - Calcium - Calcium control - Phosphate - Disorders of calcium metabolism - Measurement of calcium - Suggested further reading - Self-assessment questions - Control of carbohydrate metabolism - Glucose homeostasis - Insulin - Disorders of carbohydrate metabolism - The investigation of glucose disorders - Suggested further reading - Self-assessment questions - Processing - Enzymes - Isoenzymes and isoforms - Clinically important enzymes - Enzymes and tissue damage - Principles of enzyme measurements - Biosensors - Suggested further reading - Self-assessment questions - Inborn errors of metabolism - Inheritance - Investigation of IBEM - Prenatal diagnosis - Phenylketonuria - Cystic fibrosis - Chromatography - Suggested further reading - Self-assessment questions - Transport and storage - Plasma proteins - Total protein - Protein groups - Specific proteins - Measurement of plasma proteins - Suggested further reading - Self-assessment questions - Lipids and lipoproteins - Lipids and lipoproteins - Lipid transport - Lipid disorders - Atherosclerosis - Laboratory investigations of lipid - Suggested further reading - Self-assessment questions - Acid-base balance and blood gases - Control of pH - Normal pH - Disorders of acid-base balance - Pathophysiology - Anion gap - Blood gases - Blood gas measurements - Suggested further reading - Self-assessment questions - Defence - Immunoglobulins - Antibodies - Disorders associated with antibodies - Laboratory investigation of antibodies - Laboratory techniques in the investigation of antibodies - Suggested further reading - Self-assessment questions - Proteins of the innate immune system - Complement proteins - Acute-phase proteins - Interferons - Clinical biochemistry and the innate immune system - Suggested further reading - Self-assessment questions - Output - Kidney function - Kidney structure and function - Kidney disease - Glomerular function - Tubular function - Proteinuria - Renal stones - Suggested further reading - Self-assessment questions - Liver function - Liver structure - Bilirubin metabolism - Jaundice - Liver disease - Investigation of liver disease - Suggested further reading - Self-assessment questions - Answers to self-assessment questions - Index