An introduction to medicinal chemistry /

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For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actual...

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Bibliographic Details
Main Author: Patrick, Graham L.
Format: Printed Book
Language:English
Published: Oxford ; New York : Oxford University Press, 2001.
Edition:2nd ed.
Subjects:
Pharmaceutical chemistry
Online Access:https://india.oup.com/product/an-introduction-to-medicinal-chemistry-9780198796589?
Table of Contents:
  • Chapters 1. Drugs and drug targets: an overview
  • Part A - Drug Targets, Pharmacodynamics and Pharmacokinetics
  • 2. Protein structure and function
  • 3. Enzymes and enzyme inhibitors
  • 4. Receptors, agonists and antagonists
  • 5. Receptors and signal transduction
  • 6. Nucleic acids as drug targets
  • 7. Miscellaneous drug targets
  • 8. Pharmacokinetics and related topics
  • Part B - Drug Discovery, Design, and Development
  • 9. Drug discovery: finding a lead
  • 10. Drug design: optimizing target interactions
  • 11. Drug design: optimizing access to the target
  • 12. Getting the drug to market
  • Part C - Selected Topics in Medicinal Chemistry
  • 13. Cholinergics, anticholinergics, and anticholinesterases
  • 14. Drugs acting on the adrenergic nervous system
  • 15. Opioid analgesics
  • 16. Antiulcer agents
  • 17. Antibacterial agents
  • 18. Antiviral agents
  • 19. Anticancer agents
  • Part D - Tools of the Trade
  • 20. Combinatorial synthesis
  • 21. Computers in medicinal chemistry
  • 22. Quantitative structure-activity relationships (QSAR)

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