Alcohol intake and oral cavity cancer risk among men in a prospective study in Kerala,India

Objective: The aim of the study was to evaluate the role of alcohol drinking and patterns of consumption in oral cancer incidence and mortality in a cohort study using data from the Trivandrum Oral Cancer Screening Study, India. Methods: At baseline, the study participants completed a lifestyle ques...

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Bibliographic Details
Main Author: Cancela M de C, Ramadas K, Fayette J-M, Thomas G, Muwonge R, Chapuis F, Thara S, Sankaranarayanan R, Sauvaget C.
Format: Printed Book
Published: Community Dentistry and oral epidemiology 2009 2009
Online Access:http://10.26.1.76/ks/003311.pdf
LEADER 019790000a22001330004500
100 |a Cancela M de C, Ramadas K, Fayette J-M, Thomas G, Muwonge R, Chapuis F, Thara S, Sankaranarayanan R, Sauvaget C. 
245 |a Alcohol intake and oral cavity cancer risk among men in a prospective study in Kerala,India 
260 |c 2009 
260 |b Community Dentistry and oral epidemiology 2009 
520 |a Objective: The aim of the study was to evaluate the role of alcohol drinking and patterns of consumption in oral cancer incidence and mortality in a cohort study using data from the Trivandrum Oral Cancer Screening Study, India. Methods: At baseline, the study participants completed a lifestyle questionnaire including items on frequency and duration of alcohol consumption. They were followed up for oral cancer incidence and mortality. Data from 32 347 subjects, of whom 134 eventually developed oral cancer, were analysed to estimate risk of oral cancer incidence and mortality according todrinking patterns, using a Cox regression model adjusted for age, religion, education, occupation, body mass index (BMI), standard of living index, chewing habits, smoking habits, and vegetable and fruit intake. Results: Current and past drinkers were each associated with significantly increased risk of developing oral cancer. The hazard ratio increased significantly by 49 per cent (95per cent CI = 1-121per cent) among current drinkers and among past drinkers. A significant dose-response relationship between intake frequency, duration and oral cancer risk (incidence and mortality) was observed. Conclusions: As with other lifestyle factors, alcohol intake plays an important role in oral carcinogenesis in this population, and understanding this role is relevant to developing public health policies targeting at-risk population. 
856 |u http://10.26.1.76/ks/003311.pdf 
942 |c KS 
999 |c 72699  |d 72699 
952 |0 0  |1 0  |4 0  |7 0  |9 64663  |a MGUL  |b MGUL  |d 2015-08-01  |l 0  |r 2015-08-01  |w 2015-08-01  |y KS 

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