Sommario:
  • 1. Historical Perspective : the Seven Ages of Cell Death Research
  • 2. The Intrinsic Apoptotic Pathway
  • 3. Molecular Basis of Cell Death Programs in Mature T Cell Homeostasis
  • 4. Bcl-2 family and their therapeutic potential
  • 5. IAP proteins and their therapeutic potential
  • 6. Cell Death and Cancer
  • 7. The DNA damage response mediates apoptosis and tumor suppression
  • 8. Neuronal Death Mechanisms in Development and Disease
  • 9. The Complex Interplay Between Metabolism and Apoptosis
  • 10. Programmed Necrosis/Necroptosis: An Inflammatory Form of Cell Death
  • 11. Structural Perspectives on BCL-2 Family of Proteins
  • 12. Structural basis of death receptor signaling.