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D-GALACTOSE INDUCED ACCELERATED AGEING A BRIEF REVIEW
Chronic exposure of house flies, fruit flies, rats and mice to D- galactose cause acceleration of ageing, The major changes include shortening of life spans in flies, increase in oxidative stress,neuro degeneration, mitochondrial dysfunction, loss of immune function and disorder in gene expression i...
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| Format: | Journal Article |
| Published: |
Ageing and society: The Indian journal of gerontology
2013
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| Online Access: | http://10.26.1.76/ks/007020.pdf |
| Summary: | Chronic exposure of house flies, fruit flies, rats and mice to
D- galactose cause acceleration of ageing, The major changes
include shortening of life spans in flies, increase in oxidative stress,neuro degeneration, mitochondrial dysfunction, loss of immune function and disorder in gene expression in mice and rats. The above cited observations simulate the changes associated with natural ageing. They also provide support to two important theories of ageing i.efree radical theory and glycation theory. |
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| Physical Description: | Vol. XXIII No. I & II, Jan - March, April - June, 2013 |