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Antibody Engineering A Practical Approach
Recombinant DNA techniques have revolutionized the isolation and production of antibodies. This volume describes methods and technologies which will allow the researcher to isolate a new antibody, analyse its properties, format the correct antibody or fragment, and produce sufficient quantities for...
| 1. Verfasser: | |
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| Format: | Printed Book |
| Veröffentlicht: |
New York
IRL PRESS
1996
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| Schriftenreihe: | Practical approach series, 169.
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| Schlagworte: | |
| Online Zugang: | http://classify.oclc.org/classify2/ClassifyDemo?owi=806987544 |
| LEADER | 02020nam a2200181 4500 | ||
|---|---|---|---|
| 999 | |c 123565 |d 123561 | ||
| 020 | |a 9780199635924 | ||
| 082 | |a 615.37 HOO/A | ||
| 100 | |a McCafferty,John;Ed. |a Hoogenboom, H R; Ed. |9 60816 | ||
| 245 | |a Antibody Engineering |b A Practical Approach | ||
| 260 | |a New York |b IRL PRESS |c 1996 | ||
| 300 | |a 325p. | ||
| 490 | |a Practical approach series, 169. | ||
| 520 | |a Recombinant DNA techniques have revolutionized the isolation and production of antibodies. This volume describes methods and technologies which will allow the researcher to isolate a new antibody, analyse its properties, format the correct antibody or fragment, and produce sufficient quantities for experimental use. Topics in this volume include: generation and analysis of antibodies; antibody repertoires; antibody screening and selection; measuring antibody affinities; sequence analysis; antibody engineering and production; conversion of rodent antibodies to human antibodies by CDR grafting or guided selection; choosing and optimizing effector functions; preparation and use of antibody-based molecules in eukaryotic and prokaryotic systems; scaling up manufacture; and generation of high-affinity high-specificity human antibodies in appropriate formats. Antibody Engineering is a unique manual of recombinant DNA methods for all those working with antibodies in research, diagnostics, and therapeutics. Each chapter is written by a leading researcher in the field and provides essential background information, fully tested protocols, sample data from using these methods, trouble-shooting comments, and key hints and tips for success. | ||
| 650 | |a Immunoglobulins -- Synthesis -- Laboratory manuals-- Genetic engineering -- Laboratory manuals-- Antibody Formation. |9 60817 | ||
| 856 | |u http://classify.oclc.org/classify2/ClassifyDemo?owi=806987544 | ||
| 942 | |c BK | ||
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