Optimal high-throughput screening : practical experimental design and data analysis for genome-scale RNAi research /

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"This book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening experiments from a statistically sound basis"--Provided by publisher.

Bibliographic Details
Main Author: Zhang, Xiaohua Douglas
Format: Printed Book
Published: Cambridge: Cambridge University Press, 2011.
Subjects:
High-Throughput screening assays-Methods.
RNA interference.
Research design.
Statistics as topic-Methods.
Online Access:https://books.google.co.in/books?id=CSxUAZo6eZEC&pg=PR4&dq=Optimal+high+throughput+screening+Xiaohua&hl=en&sa=X&ved=0ahUKEwiY-qO3t7PWAhVFOI8KHS9jBFcQ6AEIJTAA#v=onepage&q=Optimal%20high%20throughput%20screening%20Xiaohua&f=false
Table of Contents:
  • Machine generated contents note: Part I. RNAi HTS and Data Analysis: 1. Introduction to genome-scale RNAi research; 2. Experimental designs; 3. Data display and normalization; 4. Quality control in genome-scale RNAi screens; 5. Hit selection in genome-scale RNAi screens without replicates; 6. Hit selection in genome-scale RNAi screens with replicates; Part II. Methodological Development for Analyzing RNAi HTS Screens: 7. Statistical methods for group comparison; 8. Statistical methods for assessing the size of siRNA effects.

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