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Molecular biology in medicinal chemistry

Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, mol...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: T h Dingermann
অন্যান্য লেখক: Dingermann, Theodor, Steinhilber, Dieter, Folkers, Gerd
বিন্যাস: Printed Book
প্রকাশিত: Weinheim : Wiley-VCH, 2004
সংস্করন:1. Aufl.
বিষয়গুলি:
অনলাইন ব্যবহার করুন:http://www.loc.gov/catdir/toc/wiley051/2004351376.html
http://www.loc.gov/catdir/enhancements/fy0621/2004351376-b.html
http://www.loc.gov/catdir/enhancements/fy0621/2004351376-d.html
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245 0 0 |a Molecular biology in medicinal chemistry  
250 |a 1. Aufl. 
260 |a Weinheim :  |b Wiley-VCH,  |c 2004 
300 |a xxi, 413 p. :  |b ill. ; 
505 0 |a Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology. 
520 |a Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action. 
650 0 |a Molecular biology. 
650 0 |a Molecular pharmacology. 
650 0 |a Pharmacogenomics. 
650 0 |a Genomics. 
650 0 |a Chiral drugs. 
700 1 |a Dingermann, Theodor. 
700 1 |a Steinhilber, Dieter, 
700 1 |a Folkers, Gerd. 
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856 4 2 |u http://www.loc.gov/catdir/enhancements/fy0621/2004351376-d.html 
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