Pharmacokinetics in drug discovery and development /

Bibliographic Details
Main Author: Schoenwald, Ronald D.
Format: Printed Book
Published: Boca Raton : CRC Press, c2002.
Subjects:
Drug development.
Online Access:http://www.loc.gov/catdir/toc/fy031/2001052887.html
http://www.loc.gov/catdir/enhancements/fy0646/2001052887-d.html
Table of Contents:
  • Machine generated contents note: SECTION I Basic Principles
  • Chapter 1 Basic Principles3
  • Ronald D. Schoenwald
  • SECTION II Industrial and Regulatory Applications
  • Chapter 2 PK/PD Approach33
  • Honghui Zhou
  • Chapter 3 Pharmacokinetics and Metabolism in Drug Discovery
  • and Preclinical Development57
  • Nishit B. Modi
  • Chapter 4 Phase I, II, and III FDA Submissions 73
  • Mark G. Eller
  • Chapter 5 Bioavailability and Bioequivalence 97
  • Veneeta Tandon
  • SECTION III Clinical Applications
  • Chapter 6 General Approaches to Clinical Pharmacokinetic Monitoring 115
  • Ronald A. Herman
  • Chapter 7 Aminoglycosides and Other Antibiotics 127
  • Michael E. Klepser and Erika J. Ernst
  • Chapter 8 Cardiovascular Agents139
  • John M. Dopp and Bradley G. Phillips
  • Chapter 9 Psychotropic Agents 171
  • Paul J. Perry
  • Chapter 10 Theophylline201
  • Bernd Meibohm
  • Chapter 11 Anticonvulsant Agents 231
  • Gail D. Anderson
  • SECTION IV Research Applications
  • Chapter 12 Classical Modeling267
  • David W A. Bourne
  • Chapter 13 Noncompartmental Modeling: An Overview 283
  • Ronald A. Herman
  • Chapter 14 Physiologically Based Pharmacokinetic Models 295
  • James M. Gallo
  • Chapter 15 Population Pharmacokinetics315
  • Jeffrey S. Barrett
  • Chapter 16 The Linear Systems Approach 357
  • Peter Veng-Pedersen
  • Index415.

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