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Bacteria versus antibacterial agents: an integrated approach/

Bibliographic Details
Main Author: Mascaretti, Oreste A.
Format: Printed Book
Published: Washington, D.C. : ASM Press, c2003.
Subjects:
Table of Contents:
  • Structure and function of prokaryotic and eukaryotic cells
  • Bacterial pathogenesis
  • Essentials of the immune system
  • Molecular genetics of bacteria
  • Mechanisms of bacterial resistance to the action of antibacterial agents
  • Antibiotics and synthetic antibacterial agents
  • Beta-lactams, and penicillin-binding proteins, and beta-lactamases
  • Inhibitors of peptidoglycan biosinthesis : penicillins
  • Inhibitors of peptidoglycan biosynthesis : cephalosporins
  • Inhibitors of peptidoglycan biosynthesis : carbapenems and monobactams
  • Beta-lactam compounds as beta-lactamase inhibitors
  • Bacterial resistance to beta-lactam antibiotics and beta-lactam inhibitors of beta-lactamases
  • Inhibitors of peptidoglycan biosynthesis : fosfomycin and d-cycloserine
  • Inhibitors of peptidoglycan biosynthesis : bacitracin and glycopeptides
  • Antibiotics that affect membrane permeability : cyclic peptides
  • Antibiotic inhibitors of bacterial protein synthesis
  • Inhibitors of the 30s ribosomal subunit : aminoglycosides and tetracyclines
  • Inhibitors of the 50s ribosomal subunit : macrolides, lincosamides and streptogramins
  • An inhibitor of the 50s ribosomal subunit : chloramphenicol
  • Inhibitors of the formation of the first peptide bond : oxazolidinones
  • An inhibitors of isoleucyl-tRNA synthetase : mupirocin
  • Inhibitors of DNA-dependent RNA polymerase : rifamycins
  • Inhibitors of DNA gyrase and topoisomerase IV : quinolones
  • Antibacterial agents that cause DNA damage in obligate anaerobic organisms : 5-nitroimidazoles
  • Antibacterial agents that cause damage to DNA : 5-nitrofurans
  • Compounds that interfere with tetrahydrofolic acid biosynthesis : sulfonamides and trimethoprim
  • New antibacterial drugs in development that act on novel targets.